I find it fairly easy to set up in LR by doing the following:
-go to HSL mode set all the Saturation sliders to -1''
-open a brush, set the Saturation setting to 1''
paint back in the colour. No Problemo...
I have a preset that I made that is called "B&W_HSL_desaturate". All it does is the first step above. It's an alternate way to convert to B&W. It's advantage is that all the color sliders color temp/tint, vibrance, saturation that disappear when you go "Grayscale" within LR are still available in this B&W mode (not that you NEED them, but I find myself playing with the Temp mostly)