In that situation I would exclude the previews and keep the others.
In a network sync situation, there are two problems with the …previews.lrdata file. One is that it can be huge (many gigabytes), which takes up time on its own, especially if the Internet connection’s upload speed is not great. The other, less commonly known reason is that it isn’t a single file, but a collection of much smaller files. On the Mac it’s in macOS “package” format (you can right-click it and choose Show Package Contents), and on Windows I think it’s a folder of files. When I run Show Package Contents on my previews.lrdata file, I see it contains over 100,000 small files. This is because each image that has a preview built might be represented by several files: a 1:1 preview, Standard preview, thumbnail preview for the Grid, etc.
This extremely large number of files means there is a tremendous amount of overhead involved in transferring the whole thing, which slows down the transfer even more. It always takes more time to manage the transfer of the same amount as many small files instead of a few large files, even locally. It's like having 40 people to move between locations, and the difference between being provided one 40-seat bus or 10 cars. The 10-car solution needs 9 more drivers, a lot more parking space, and more coordination.
Excluding the previews means each computer needs to generate and maintain its own previews, but I think that’s a smaller price to pay than when trying to sync previews over the Internet. I doubt it’s a problem with ChronoSync, this would probably happen with any sync software.